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WAM Essentials, Inc.
Systemic Enzyme Therapy
... Allowing You to Live Your Passion!™ |
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Therapy of
adnexitis - enhancement of the basic antibiotic therapy with
hydrolytic enzymes
Dittmar F.-W.1, Weissenbacher E. R.2
1 Department of Obstetrics and Gynecology, District Hospital
Starnberg, Teaching Hospital of the Ludwig-Maximilians-University
Munich, W-8130 Starnberg, FRG
2 Gynecologic Clinic, Clinic Center Großhadern, Ludwig-Maximilians-University
Munich, W-8000 Munich 70, FRG
International Journal of Experimental and Clinical Chemotherapy
1992: Vol. 5, No. 2, pp. 73-81
WE 12 (5-03-2) = WE 44 (5-04-2) nem.
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Abstract
A total of 56 patients were recruited to a randomized double
blind study (28 to the enzymes and placebo group, respectively)
and treated for a period of 28 days in order to evaluate
the effectiveness and tolerance of an enzyme combination
preparation as adjuvant of the initial 6-day basic
antibiotic treatment.
At the beginning of the investigation there were no
differences between the enzymes and the placebo group
regarding the parameters characterizing the process
of recovery. At the end, however, such differences
were observed: body temperature in the enzymes group
37.0°C, in the placebo group 37.2°C, p = 0.021;
WBC in the enzymes group 8,800/m l, in the placebo group 10,100/m
l, p = 9.52 x 10-6; ESR after 1 h 14.8 mm/h and 19.5 mm/h in
the enzymes and placebo group, respectively, p = 0.003; score
for palpable tumors in the enzymes group 1.0 ("more resistant
to touch than normal on one side") and 3.0 in the placebo
group ("bilateral resistance to touch"), p = 1.28
x 10-7; score for tenderness on pressure in the enzymes group
0 (nothing abnormal detected) and 2 in the placebo group (uterus
and adnexa), p = 4.42 x 10-7; score for vaginal discharge in
the enzymes group 0 ("white/normal") and 1 in the
placebo group ("slightly purulent and/or sanguineous"),
p = 1.39 x 10-6.
The adnexitis score, defined as major criterion of effectiveness,
gave corresponding results: with comparable baseline values
(enzymes = 12.2, placebo = 11.3, p = 0.08) it was 2.6 in
the enzymes group (subacute adnexitis) and 7.7 in the placebo
group (moderate adnexitis) at the end of therapy (p = 7.45
x 10-7).
The results of this study suggest that the enzyme combination
preparation used is effective as adjuvant of basic antibiotic
treatment in acute adnexitis. There were no side effects
in either group.
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© Copyright 2004 WAM Essentials,
Inc. All Rights Reserved.
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